The Women's Postgraduate College for Internet Technologies (WIT) and the Faculty of Informatics of the Vienna University of Technology and the Austrian Computer Society (OCG) invited to:
A Grand Challenge: Full Reactive Modeling of a Multi-Cellular Animal
After the event
A video of the lecture was produced but is only available for internal use at the Technical University of Vienna.
Biological systems exhibit the characteristics of reactive systems
remarkably, and on many levels; from the molecular, via the cellular,
and all the way up to organs, full organisms, and even entire populations.
Thus, a different brand of bioinformatics arises, in which, rather than
"we" solving "their" computational problems, we
use "our" languages, methods and tools to model and analyze
"their" complex systems. This talk proposes a grand challenge
for computer scientists and biologists: to model a full multi-cellular
animal as a reactive system. We would like to construct a full, true-to-all-known-facts
4-dimensional model, that would be animated, flexible and comprehensive,
and would enable full and realistic simulation of the animal's development
and behavior over time (the fourth dimension). The talk will argue the
(long-term) feasibility of the challenge, by describing two pieces of
preliminary modeling work: (i) T-cell behavior in the thymus, using
statecharts with Rhapsody, linked with Flash animation, and (ii) parts
of the vulval development of C. elegans, using LSCs with the Play-Engine.
David Harel has been a faculty member at the Weizmann Institute of
Science in Israel since 1980. He was Head of the Department of Applied
Mathematics and Computer Science from 1989 to 1995, and was Dean of
the Faculty of Mathematics and Computer Science between 1998 and 2004.
He is also co-founder of I-Logix, Inc. He received his PhD from the
Massachusetts Institute of Technology in 1978. He has spent two years
at IBM's Yorktown Heights research center, and sabbatical years at Carnegie-Mellon
and Cornell Universities.
Contact person at Vienna University of Technology
Dr. Beate List, firstname.lastname@example.org , Tel. 58801-18830
WIT is funded by the Austrian Federal Ministry for Education, Science, and Culture (bmbwk) and the European Social Fund (ESF). This event is sponsored by Erste Bank.
© 2004 by WIT, last modified: